Review of Cancer Risk and Hormone Therapy

breast cancer hormone therapy

“Women and their healthcare providers should feel reassured about the safety of hormone therapy when used at menopause.”

Joanne pinkerton, MD, FACOG, NCMP
professor of obstetrics and gynecology, director of midlife health at UVA Health and executive director emeritus of the North American Menopause Society

A new review examined trial and observational study data and concluded that when prescribed to women after a hysterectomy, estrogen therapy used alone at menopause did not increase the risk of invasive breast cancer. Longer durations of estrogen therapy use may increase risk. For women who still have their uterus and use combined estrogen and progestogen, especially long-term, breast cancer risk increased slightly but did not translate into a higher risk of death.

Authors of an editorial, including the past medical director of the North American Menopause Society, recommend that patients and their doctors reevaluate whether to continue the treatment periodically while continuing with breast examinations and breast imaging. 


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